Table 3. Serum Biomarkers.

Analyte	Cases	Controls	p
pg/mL	N = 70	N = 123
MMP-1 *	387(116–864)	775(296–1368)	0.001
MMP-2	2840(1281–5130)	3020(1815–4640)	0.268
MMP-3 *	3194(1962–7542)	7653(3320–13765)	<0.001
MMP-7	293(67–396)	222(96–320)	0.382
MMP-8 *	2(2–20)	2(2–174)	0.030
MMP-9	25610(12222–74000)	23490(11196–47084)	0.548
MMP-12 *	35(7–218)	66(22–313)	0.008
MMP-13	58(9–109)	75(3–141)	0.355

^*p<0.05; All values shown as median (IQR).