Skip to main content
. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Hum Genet. 2013 Jun 23;132(11):1235–1243. doi: 10.1007/s00439-013-1325-0

Fig 3. Glutathione S-transferase in complex with platinum and ethacrynic acid conjugated with glutathione.

Fig 3

A PharmGKB polymorphic variant known to be associated with resistance to platinum compound toxicity (green) can be seen proximal to the binding site of glutathione (pink). Glutathione, ethacrynic acid and platinum are shown as ball and stick.