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(A) Transmission electron microscopy (TEM) micrographs of T. forsythia ultrathin sections. (B) Schematic diagram of the O-glycan core structure linked to a peptide motif in Tannerella surface-layer proteins. A terminal trisaccharide motif synthesized by the wecC operon is circled. (C) Signaling crosstalk between a C-type lectin-like receptor (CLR) and TLR2 activated by O-glycans and TLR2 ligands (e.g., BspA), respectively, may orchestrate T helper cell differentiation.
