Table 1.
Sociodemographic and clinical characteristics of the two neurocognitive groups of patients.
| Characteristics | Non-deficit (N = 29) | Deficit (N = 30) | Statistics |
|---|---|---|---|
| Age at initial MRI, mean (SD), years | 28.50 (6.93) | 32.12 (9.97) | F(1, 57) = 2.59, p = 0.113 |
| ICV, mean (SD) | 1367.41 (128.78) | 1343.19 (120.18) | F(1, 57) = 0.56, p = 0.458 |
| Males, N (%) | 18 (62.1) | 20 (66.7) | χ2(1) = 1.36, p = 0.712 |
| Time between scans, mean (SD), (range) days | 1117.96 (39.58) | 1120.63 (56.34) | F(1, 57) = 0.04, p = 0.835 |
| Right-handed, N (%) | 26 (89.7) | 25 (83.3) | χ2(1) = 0.50, p = 0.478 |
| Parental socioeconomic status, mean (SD) | 3.45 (0.87) | 3.60 (0.89) | F(1, 57) = 0.44, p = 0.512 |
| Years of study, mean (SD) | 10.89 (3.17) | 10.13 (3.19) | F(1, 57) = 0.85, p = 0.360 |
| Alcohol users, N (%) | 17 (58.6) | 19 (63.3) | χ2(1) = 1.38, p = 0.711 |
| Cannabis users, N (%) | 15 (51.7) | 11 (36.7) | χ2(1) = 1.35, p = 0.244 |
| Tobacco users, N (%) | 17 (58.6) | 16 (53.3) | χ2(1) = 0.17, p = 0.683 |
| Age at onset, mean (SD), years | 27.61 (6.28) | 30.59 (9.79) | F(1, 57) = 1.91, p = 0.172 |
| DUP mean, (SD), (median), months | 10.74 (19.39) | 18.35 (21.15) | F(1, 57) = 2.07, p = 0.155 |
| DUI mean, (SD), (median), months | 28.32 (32.79) | 30.45 (29.54) | F(1, 57) = 0.07, p = 0.794 |
| SANS at intake, mean (SD) | 6.55 (4.95) | 7.13 (5.37) | F(1, 57) = 0.19, p = 0.667 |
| SANS at follow up, mean (SD) | 1.89 (2.96) | 3.34 (4.57) | F(1, 55) = 2.00, p = 0.162 |
| SAPS at intake, mean (SD) | 13.44 (4.44) | 13.67 (4.17) | F(1, 57) = 0.04, p = 0.846 |
| SAPS at follow up, mean (SD) | 0.57 (1.40) | 2.86 (4.62) | F(1, 55) = 6.30, p = 0.015 |
| BPRS at intake, mean (SD) | 62.00 (11.67) | 63.50 (13.68) | F(1, 57) = 0.21, p = 0.653 |
| BPRS at follow-up, mean (SD) | 27.14 (4.33) | 32.93 (14.17) | F(1, 55) = 4.28, p = 0.043 |
| SYMPTOM DIMENSIONS TOTAL SCORES AT BASELINE | |||
| Negative (mean) (SD) | 4.75 (4.69) | 5.40 (4.90) | F(1, 57) = 0.26, p = 0.610 |
| Disorganized (mean) (SD) | 6.07 (3.43) | 6.10 (3.35) | F(1, 57) < 0.01, p = 0.972 |
| Psychotic (mean) (SD) | 7.37 (2.38) | 7.57 (2.31) | F(1, 57) = 0.09, p = 0.760 |
| SYMPTOM DIMENSIONS TOTAL SCORES AT FOLLOW UP | |||
| Negative (mean) (SD) | 1.54 (2.33) | 2.90 (4.25) | F(1, 55) = 2.23, p = 0.141 |
| Disorganized (mean) (SD) | 0.25 (0.84) | 1.45 (2.99) | F(1, 55) = 4.16, p = 0.046 |
| Positive (mean) (SD) | 0.32 (1.19) | 1.41 (2.06) | F(1, 55) = 5.95, p = 0.018 |
BPRS, brief psychiatric rating scale; DUP, duration of untreated psychosis; DUI, duration of untreated illness; ICV, intracranial volume; SANS, scale for the assessment of negative symptoms; SAPS, scale for the assessment of positive symptoms; SD, standard deviation. Bold values were statistically significant (p < 0.05).