Figure 4. Increased expression of Ptges in the skin of mice and humans as a result of niacin deficiency.

(A) The levels of mRNA were measured and expressed as relative quantities normalized to Actb. ND, not detectable. (B) Skin specimens taken from healthy subjects (n = 3) and patients with pellagra (n = 3) were immunostained with anti-PTGES antibody. Representative samples are shown. Scale bar 100 μm. (C; D) The number and percentage of PTGES positive cells were counted. Data are presented as means ± SEM. *, P < 0.05. HPF, high power field.