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. Author manuscript; available in PMC: 2013 Oct 17.
Published in final edited form as: Cell. 2001 Apr 6;105(1):25–42. doi: 10.1016/s0092-8674(01)00294-x

Figure 8.

Figure 8

Novel and Mixed Phenotypes of Clock/Clock Chimeras Annotated on a Cluster Analysis of Regional SCN Scores Single linkage hierarchical cluster analysis was used. The cluster tree diagram for the cellular genotype distribution patterns is on the vertical axis of the matrix. SCN LacZ staining increases from the top to the bottom—scores 1–5 indicate fewer to more WT cells. Cluster analysis applied to the 12 SCN regional variables is shown in the dendrogram on the horizontal axis of the matrix. Abbreviations for SCN regions: D = dorsal, V = ventral, L = left, R = right, A = anterior, M = medial, P = posterior. Instances of chimeras that behave as Clock heterozygote phenocopies, animals that show labile rhythmicity, and those that exhibit the short, low-amplitude mixed phenotype are annotated to the left of the matrix.