Table 4.
Positive and Negative predictive values of combination of TTE and PFT parameters
| eRVSP>35mmHg | eRVSP >40mmHg | eRVSP > 45mmHg | eRVSP > 50mmHg | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PFT parameters | PPV | NPV | Sens | Spec | PPV | NPV | Sens | Spec | PPV | NPV | Sens | Spec | PPV | NPV | Sens | Spec |
| FVC%/DLCO%≥1.6 | 0.433 | 0.978 | 0.970 | 0.512 | 0.508 | 0.982 | 0.970 | 0.638 | 0.508 | 0.966 | 0.940 | 0.649 | 0.513 | 0.951 | 0.910 | 0.669 |
| FVC%/DLCO%≥1.8 | 0.455 | 0.980 | 0.970 | 0.551 | 0.546 | 0.984 | 0.970 | 0.689 | 0.553 | 0.969 | 0.940 | 0.707 | 0.560 | 0.948 | 0.896 | 0.730 |
| FVC%/DLCO%≥2.0 | 0.492 | 0.982 | 0.970 | 0.615 | 0.643 | 0.986 | 0.970 | 0.793 | 0.655 | 0.947 | 0.882 | 0.822 | 0.687 | 0.937 | 0.851 | 0.851 |
| DLCO < 60% | 0.436 | 0.978 | 0.970 | 0.517 | 0.500 | 0.982 | 0.970 | 0.626 | 0.500 | 0.965 | 0.940 | 0.649 | 0.508 | 0.966 | 0.940 | 0.649 |
| DLCO < 70% | 0.369 | 0.969 | 0.970 | 0.362 | 0.406 | 0.975 | 0.970 | 0.454 | 0.403 | 0.963 | 0.955 | 0.454 | 0.408 | 0.964 | 0.955 | 0.465 |
eRVSP= estimated right ventricular systolic pressure in mmHg FVC/DLCO= Forced vital capacity/diffusion of the lung for carbon monoxide percent predicted ratio, DLCO= diffusion capacity for the lung percent predicted. PPV= positive predictive value, NPV= negative predictive value, Sens= sensitivity, Spec= specificity.