Table 1.
Serum lipid profile of ApoE−/−/EC-SREBP2(N) and their ApoE−/− littermates fed a normal chow or atherogenic diet.
Serum Lipids (mg/dL) | Normal Chow* | Atherogenic Diet† | ||
---|---|---|---|---|
ApoE−/−(n = 7) | ApoE−/−/EC-SREBP2(N) (n = 6) | ApoE−/−(n = 17) | ApoE−/−/EC-SREBP2(N) (n = 18) | |
Total cholesterol | 1284 ± 272‡ | 1224 ± 334 | 1806 ± 298 | 1967 ± 576 |
Triglyceride | 169 ± 49 | 197 ± 112 | 111 ± 57 | 125 ± 89 |
LDL | 490 ± 54 | 478 ± 83 | 1055 ± 168 | 1035 ± 235 |
VLDL | 30 ± 14 | 39 ± 22 | 21 ± 12 | 29 ± 22 |
HDL | 764 ± 253 | 707 ± 374 | 730 ± 177 | 903 ± 365 |
Normal chow group was 24-week old mice fed a normal chow.
Atherogenic diet group was 8-week old mice fed an atherogenic diet for 8 weeks.
All values are expressed as mean ± SD averaged from number of animals as indicated.