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. Author manuscript; available in PMC: 2013 Nov 26.

Published in final edited form as: J Med Chem. 2012 Nov 8;55(22):9669–9681. doi: 10.1021/jm300908t

Simplified analysis of the structural features of the CAI-1 family of QS signal molecules. An equivalent of SAM (3) is incorporated into CAI-1 providing the structurally conserved portion of the final molecules (highlighted in red), along with an equivalent of a fatty acid in the form of a fatty acid thioester that provides the structurally variable portion of the signaling molecules (highlighted in blue). ( = fatty acid; R′ = CoA or ACP)

Inline graphic — Simplified analysis of the structural features of the CAI-1 family of QS signal molecules. An equivalent of SAM (3) is incorporated into CAI-1 providing the structurally conserved portion of the final molecules (highlighted in red), along with an equivalent of a fatty acid in the form of a fatty acid thioester that provides the structurally variable portion of the signaling molecules (highlighted in blue). ( = fatty acid; R′ = CoA or ACP)