TABLE III.
UCT Matching, TNC, and Engraftment
| Period 1a | Period 2b | Period 3c | Total | ||
|---|---|---|---|---|---|
| Total allogeneic transplants | 41 | 48 | 47 | 136 | P-value |
| UCTd | 0 | 8 | 21 | 29 | <0.001 |
| 4/6 match | 4 (50%) | 2 (10%) | 6 (20.7%) | 0.028 | |
| 5/6 match | 2 (25%) | 11 (52.4%) | 13 (44.8%) | 0.23 | |
| 6/6 match | 2 (25%) | 4 (19%) | 6 (20.7%) | 0.75 | |
| Double cord transplante | 0 | 4 (19%) (3 × 5/6 match, 1 × 4/6) | 4 (13.8%) | ||
| Median TNCf (range) | 3.35 (0.6–5.0) | 4.7 (0.5–8.4) | 4.7 (0.5–8.4) | 0.08 | |
| Median neutrophil engraftment (days, range) | 25.5 (18–34) | 16 (6–33) | 20 (6–34) | 0.014 | |
| Median platelet engraftment (days, range) | 60.5 (19–84) | 40.5 (23–91) | 46 (19–91) | 0.64 | |
| Median hospital days (range) | 41 (29–87) | 45 (29–80) | 42 (29–87) | 0.16 |
a
Period 1: 1/1/1984–31/8/1992
b
Period 2: 1/9/1992–30/4/2001
c
Period 3:1/5/2001–31/12/2009
d
Umbilical cord blood transplant
e
Matching for double cord transplants was according to the least matched cord
f
Total nucleated cells × 107/kg.