Table 1.
Risk Factors for E. coli Resistance to Levofloxacin.
| Category | Levofloxacin resistance, n, % (n=39) |
Levofloxacin susceptible, n, % (n=183) |
p-value |
|---|---|---|---|
| Sex, male | 13 (33.3%) | 28 (15.3%) | 0.016 |
| Race | 0.272 | ||
| White | 33 (84.6%) | 137 (74.9%) | |
| African-American | 4 (10.2%) | 26 (14.2%) | |
| Other | 2 (5.1%) | 20 (10.9%) | |
| Diabetes mellitus | 10 (25.6%) | 31 (16.9%) | 0.296 |
| Hypertension | 17 (43.6%) | 25 (13.7%) | <0.001 |
| Chronic respiratory disease | 9 (23.1%) | 7 (3.8%) | <0.001 |
| Benign prostatic hypertrophy (BPH) | 4 (10.3%) | 1 (0.6%) | 0.003 |
| Nursing home resident | 7 (17.9%) | 0 (0%) | <0.001 |
| Antibiotic use within 90 days | 26 (66.7%) | 11 (6.0%) | <0.001 |
| Previous UTI within 90 days | 22 (56.4%) | 9 (4.9%) | <0.001 |
| Renal or genito-urinary abnormality | 27 (69.2%) | 16 (8.7%) | <0.001 |
| Immunosuppression | 5 (12.8%) | 7 (3.8%) | 0.062 |
| Home use of antibiotics | 3 (7.7%) | 2 (1.1%) | 0.054 |
| Surgical procedures within 30 days | 8 (20.5%) | 7 (3.8%) | <0.001 |