Table 1.
Characteristics of hospitalized patients with sepsis, statin group and control group.
| Characteristics | All patients (n=351) | Statin group (n=106) |
Control group (n=245) | p-value |
|---|---|---|---|---|
| Age (y) | 71.33 ± 14.4 | 71.96±12.56 | 71.06 ±15.21 | 0.56 |
| Male sex (no [%]) | 195 (55.6%) | 64 (60.4%) | 131 (53.5%) | 0.232 |
| Temperature | ||||
| <36(°C) | 51 (14.5%) | 11 (10.4%) | 40 (16.3%) | 0.15 |
| >38(°C) | 76 (21.7%) | 23 (21.7%) | 53(21.6%) | 0.98 |
| Heart rate >90/min | 176 (50.1%) | 51(48.1%) | 125 (51.0%) | 0.62 |
| WBC* > 12 000/ mm3 | 279 (79.5%) | 85 (80.2%) | 194 (79.2%) | 0.83 |
| WBC*< 4000/ mm3 | 42 (12.0%) | 12 (11.3%) | 30 (12.2%) | 0.81 |
| WBC*>10% Bands | 20 (5.7%) | 2 (1.9%) | 18 (7.3%) | 0.04 |
| Respiratory rate>20/min | 213 (60.7%) | 62 (58.5%) | 151 (61.6%) | 0.58 |
| Pco2**<32 mm Hg | 224 (63.8%) | 68 (64.2%) | 156 (63.7%) | 0.93 |
| Previous diagnosis | All patients (n=311) | Statin group (n=93) | Non statin group (n=218) | P.Value |
| History of cardiovascular disease | 199 (64%) | 74 (79.6%) | 125 (57.3%) | 0.0001 |
| Arterial hypertension | 168 (54%) | 62 (66.7%) | 106 (48.6%) | 0.003 |
| Coronary artery disease | 81 (26%) | 39 (41.9%) | 42 (19.3%) | 0.0001 |
| Cerebrovascular disease | 50 (16.1%) | 24 (25.8%) | 26 (11.9%) | 0.002 |
| Cardiac failure | 40 (12.9%) | 15 (16.1%) | 25 (11.5%) | 0.261 |
| History of diabetes | 114 (36.7%) | 48 (51.6%) | 66 (30.3%) | 0.0001 |
| History of chronic kidney diseases | 57 (18.3%) | 23 (24.7%) | 34 (15.6%) | 0.06 |
| History of cancer | 27 (8.7%) | 6 (6.5%) | 21 (9.6%) | 0.362 |
| History of dyslipidemia | 60 (19.3%) | 58 (62.4%) | 3 (1.4%) | 0.0001 |
| Others*** | 152 (48.9%) | 41 (44.1%) | 111 (50.9%) | 0.27 |
| *White blood cells *Arterial carbon dioxide tension ***Dementia, cataracts, ulcers, hypothyroidism, hematological disorder, Alzheimer's, Parkinson, asthma, hepatitis, gastrointestinal bleeding, | ||||