Figure 5. Variation of most influential model parameters.

Double-logarithmic plots of cell contact radius versus time. (a) varying cell-substrate adhesion strength yields both a shift in speed and final contact radius. (b) varying the FENE stretching constant yields different final contact radii, (c) varying the FENE max strain also mostly influences the final contact radii, (d) varying bending stiffness influences both spreading speed and final contact radius, (e) varying the normal friction coefficient influences spreading speed and (f) varying the local area constraint constant influences the final spreading radius. For a comparison of spreading rates, see supplementary Figure S1.