Table 2. Univariate and multivariate analysis of clinicopathologic variable influence on DSS in Chinese cohort.

Variables	Univariate			Multivariate
	HR	95%CI	P	HR	95%CI	P
Sex
Female	1			1
Male	0.961	0.801–1.154	0.673	0.962	0.796–1.162	0.685
Age$
<52	1			1
52–61	0.963	0.757–1.224	0.756	0.930	0.728–1.189	0.564
61–68	1.282	1.017–1.616	0.035	1.274	1.003–1.618	0.047
>68	1.355	1.085–1.693	0.007	1.229	0.976–1.547	0.079
Primary location
Antrum/Pyloric	1			1
Middle Third	1.138	0.905–1.430	0.268	0.998	0.790–1.261	0.989
GE Junction	1.777	1.466–2.154	<0.0001	1.284	1.040–1.585	0.020
Proximal Third	1.472	1.128–1.920	0.004	0.973	0.736–1.286	0.846
Lauren histotype
Diffuse	1			1
Intestinal	0.786	0.655–0.943	0.009	0.846	0.698–1.025	0.088
Mixed	1.092	0.883–1.351	0.416	1.022	0.822–1.271	0.842
Size$
<3	1			1
3–4	1.435	1.075–1.917	0.014	0.969	0.718–1.309	0.839
4–6	1.829	1.426–2.347	<0.0001	1.066	0.817–1.392	0.637
>6	3.041	2.395–3.861	<0.0001	1.489	1.144–1.938	0.003
Number of positive nodes$
0	1			1
0–3	2.237	1.652–3.029	<0.0001	1.747	1.276–2.392	<0.0001
3–9	3.824	2.969–4.925	<0.0001	2.654	2.025–3.480	<0.0001
>9	6.427	4.988–8.282	<0.0001	3.670	2.773–4.858	<0.0001
Number of negative nodes$
<6	1			1
6–12	0.548	0.446–0.672	<0.0001	0.628	0.509–0.775	<0.0001
12–19	0.371	0.296–0.464	<0.0001	0.508	0.403–0.642	<0.0001
>19	0.193	0.148–0.250	<0.0001	0.309	0.234–0.408	<0.0001
Depth of tumor invasion
Mucosa	1			1
Submucosa	1.639	0.623–4.311	0.317	1.304	0.492–3.460	0.593
Propria Muscularis	2.556	1.089–5.998	0.031	1.524	0.637–3.641	0.344
Subserosa	4.865	1.849–12.802	0.001	3.253	1.215–8.708	0.019
Susp Serosal Invasion	7.152	3.161–16.180	<0.0001	2.747	1.175–6.419	0.020
Def. Serosal Invasion	7.309	3.258–16.395	<0.0001	2.639	1.136–6.129	0.024
Adjacent Organ Invasion	9.434	4.048–21.983	<0.0001	3.467	1.438–8.355	0.006

^$The values are, respectively, the 1st, 2nd, 3rd, and 4th quartiles of the variable distribution.