Table 4. The Diagnostic Power for Differentiating Gastric Carcinoma from the Controls in the Training Group.
Cutoff value |
Actual status, No. of subjects |
|||||||
---|---|---|---|---|---|---|---|---|
Test | GC+ | GC- | Sensitivity, % | Specificity, % | PPV, % |
NPV, % |
Accuracy, % | |
CEA (5 ng/mL) | GC+ | 54 | 5 | 45.76 | 95.37 | 91.53 | 61.68 | 69.47 |
GC- | 64 | 103 | ||||||
CA19-9 (37 U/mL) | GC+ | 45 | 10 | 38.14 | 90.74 | 81.82 | 57.31 | 63.27 |
GC- | 73 | 98 | ||||||
CA125 (40 U/mL) | GC+ | 22 | 7 | 18.64 | 93.52 | 75.86 | 51.27 | 54.42 |
GC- | 96 | 101 | ||||||
CA72-4 (9.8 U/mL) | GC+ | 16 | 8 | 13.56 | 92.59 | 66.67 | 49.51 | 51.33 |
GC- | 102 | 100 | ||||||
GCglycoA (-0.77) | GC+ | 89 | 16 | 75.42 | 85.19 | 84.76 | 76.03 | 80.09 |
GC- | 29 | 92 |
Abbreviations: + positive; - negative; GC, gastric carcinoma; GCglycoA, N-glycan marker-based gastric cancer diagnostic model A; NPV, negative predictive value; PPV, positive predictive value.