Table 7. The Diagnostic Power for Differentiating Gastric Carcinoma from Atrophic Gastritis in the Training Group.
Cutoff value |
Actual status, No. of subjects |
|||||||
---|---|---|---|---|---|---|---|---|
Test | GC+ | GC- | Sensitivity, % | Specificity, % | PPV, % |
NPV, % |
Accuracy, % | |
CEA (5 ng/mL) | GC+ | 54 | 19 | 45.76 | 78.65 | 73.97 | 52.24 | 59.90 |
GC- | 64 | 70 | ||||||
CA19-9 (37 U/mL) | GC+ | 45 | 17 | 38.14 | 80.90 | 72.58 | 49.66 | 56.52 |
GC- | 73 | 72 | ||||||
CA125 (40 U/mL) | GC+ | 22 | 8 | 18.64 | 91.01 | 73.33 | 45.76 | 49.76 |
GC- | 96 | 81 | ||||||
CA72-4 (9.8 U/mL) | GC+ | 16 | 8 | 13.56 | 91.01 | 66.67 | 44.26 | 46.86 |
GC- | 102 | 81 | ||||||
GCglycoB (0.594) | GC+ | 88 | 8 | 73.73 | 91.01 | 91.58 | 72.32 | 81.16 |
GC- | 30 | 81 |
Abbreviations: + positive; - negative; GC, gastric carcinoma; GCglycoB, N-glycan marker-based gastric cancer diagnostic model B; NPV, negative predictive value; PPV, positive predictive value.