Table 5.

Kaplan-Meier (KM) and Cox regression (Cox) analyses on PFS and OS in patients who received chemotherapy only

Parameters	PFS-KM			OS-KM			OS-Cox
	Median survival (days)		p	Median survival (days)		p	Hazard ratio	p
	Group 0	Group 1		Group 0	Group 1
Sex	405	227	0.590	764	710	0.767
Age	208	366	0.135	710	859	0.090
Site of primary	314	208	0.539	710	859	0.137
Haemoglobin	428	314	0.528	640	724	0.786
White cell count	339	208	0.496	859	167	0.002	0.262	0.013
Platelets	339	208	0.975	850	405	0.119
ALP	314	87	0.510	764	941	0.483
LDH	314	227	0.243	859	764	0.527
CEA	314	208	0.530	859	710	0.203
Number of mets	353	314	0.402	850	725	0.323
Response to chemotherapy	87	428	0.000	431	850	0.039	2.164	0.092
Liver lesion diameter	205	366	0.578	859	725	0.582
ADChigh	369	208	0.782	725	850	0.674

ADC, apparent diffusion coefficient; ALP, alkaline phosphatase; CEA, carcionembryonic antigen; LDH, lactate dehydrogenase; OS, overall survival; PFS, progression-free survival.

Patients who responded to chemotherapy had longer PFS. Patients whose white cells were <10 had prolonged OS.

Factors reaching statistical significance are highlighted in bold.