Figure 3. Expression of cartilage marker genes during fracture healing.

Collagen II (A) and Collagen X (B) expression in fracture calluses derived from WT and Darc-KO mice at 3, 7 and 15 days post-fracture. Data are expressed as fold change in the expression of the gene in the fractured bones compared to unfractured bone of WT mice. We analyzed 3–4 animals/mouse strain at 3 days post-surgery and 5–8 animals/mouse strain at 7 and 15 days post-fracture.*p<0.05 vs WT unfractured bones, #p<0.05 between fractured bones of the two lines of mice.