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. 2013 Oct 17;8(10):e77627. doi: 10.1371/journal.pone.0077627

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© 2013 Lenz et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Ranking of PhysioScores comparing breast cancer samples of grade 1 to grade 2 or 3 (A) and lung samples from never smokers to former or current smokers (B). Apparently, grading differences in breast cancer are associated with more signatures from the PhysioSpace than differences in gene expression of smokers and non-smokers. Blue (red) colors depict negative (positive) PhysioScores. Filled bars indicate significant scores according to a sample-permutation FDR (Benjamini-Hochberg) cutoff of 0.1.