Table 1. CDR3β sequences of islet-infiltrating CD4⁺CD44^high T cells.

	NOD mouse #	Total CDR3β sequences1	Total unique clonotypes2	Entropy3
Prediabetic	1	39,521	1,989	0.441
	2	7,147	388	0.724
	3	42,349	798	0.717
	4	46,142	7,692	0.635
	5	6,141	2,049	0.984
	6	193,763	2,822	0.896
	7	19,241	185	0.846
Total	n = 7	354,304	15,923
Diabetic	8	555	26	0.440
	9	2,468	849	0.983
	10	9,634	80	0.291
	11	1,506	139	0.673
	12	1,120	37	0.462
	13	12,990	90	0.819
	14	4,470	86	0.690
	15	627	70	0.780
	16	33,397	94	0.444
Total	n = 9	66,767	1,471

¹Total number of TCRβ CDR3 sequences amplified.

²Total number of unique clonotypes identified.

³Shannon’s entropy was used to quantify diversity of the TCRβ repertoire. Higher values indicate greater diversity.