FIGURE 4.

Model of MyD88-TIR domain homodimerization. Modeling of a MyD88-TIR dimer was performed by a computational approach using the available NMR structure as template (16) and the PatchDock and FireDock algorithms. Glu183 and Pro200 are shown on the first monomer (blue); Ser244 and Arg288 are shown on the second monomer (yellow).