Table 3. Haplotype frequencies of XRCC1, and odds ratios for pancreatic cancer associated with XRCC1 haplotype.

Haplotype	SNPsa		Haplotype frequency			Adjusted ORb (cases/controls 185/1465)	P-value
	1 (C>T)	2 (G>A)	Overall	Cases	Controls
1	C	G	0.439	0.433	0.442	1.00 (ref.)
2	C	A	0.240	0.274	0.239	1.32 (1.01–1.71)	0.042
3	T	G	0.319	0.292	0.318	1.05 (0.81–1.36)	0.691
4	T	A	0.002	<0.001	0.002	N.E.	N.E.

Abbreviation: OR, odds ratio.

^aSNP 1 is rs1799782; SNP 2 is rs25487.

^bHaplotype-effects logistic regression for case-control data was used. Multivariable adjustment by age, sex, current BMI, BMI at age 20, smoking status, drinking habit, diabetes mellitus, and family history of PC.