Table 1. Baseline characteristics of study subjects according to MET-min/week (n = 59 636): The Severance Cohort Study, 1994–2004.
| MET-min/week | P for trend | |||
| 0 | 3.5–1000 | >1000 | ||
| Men | n = 21 051 | n = 5808 | n = 4805 | |
| mean ± SD | mean ± SD | mean ± SD | ||
| Age (years) | 45.6 ± 10.6 | 47.2 ± 10.0 | 49.4 ± 10.0 | <0.0001 |
| Body mass index (kg/m2) | 24.1 ± 3.0 | 24.3 ± 2.7 | 24.5 ± 2.6 | <0.0001 |
| Systolic blood pressure (mm Hg) | 124.0 ± 18.2 | 124.3 ± 18.1 | 125.9 ± 18.9 | <0.0001 |
| Diastolic blood pressure (mm Hg) | 73.3 ± 12.0 | 73.0 ± 12.2 | 72.5 ± 12.1 | <0.0001 |
| Total cholesterol (mg/dL) | 196.4 ± 35.5 | 197.7 ± 34.2 | 198.6 ± 34.0 | <0.0001 |
| HDL cholesterol (mg/dL) | 46.2 ± 11.6 | 46.7 ± 11.5 | 47.7 ± 11.6 | <0.0001 |
| Triglyceride (mg/dL) | 170.1 ± 118.4 | 164.4 ± 109.0 | 160.6 ± 114.1 | <0.0001 |
| Fasting glucose (mg/dL) | 98.2 ± 26.5 | 98.5 ± 24.0 | 99.6 ± 25.1 | 0.0017 |
| GGT (IU/L) | 47.8 ± 68.3 | 40.1 ± 43.0 | 40.4 ± 42.3 | <0.0001 |
| AST (IU/L) | 23.9 ± 23.7 | 22.1 ± 11.6 | 22.1 ± 10.8 | <0.0001 |
| ALT (IU/L) | 30.0 ± 31.3 | 27.0 ± 21.6 | 25.5 ± 17.8 | <0.0001 |
| % | % | % | ||
| Smoking status | ||||
| Ex-smoker | 24.3 | 34.0 | 40.3 | |
| Current smoker | 56.4 | 42.5 | 39.5 | <0.0001 |
| Alcohol intake (yes) | 81.3 | 86.4 | 85.7 | <0.0001 |
| Hypertension (yes) | 24.5 | 26.0 | 29.0 | <0.0001 |
| Diabetes (yes) | 6.8 | 8.0 | 9.4 | <0.0001 |
| Women | n = 20 481 | n = 3889 | n = 3602 | |
| mean ± SD | mean ± SD | mean ± SD | ||
| Age (years) | 47.4 ± 10.8 | 48.3 ± 10.2 | 47.5 ± 9.2 | 0.0398 |
| Body mass index (kg/m2) | 23.5 ± 3.3 | 23.4 ± 3.0 | 23.6 ± 2.8 | 0.7922 |
| Systolic blood pressure (mm Hg) | 121.8 ± 21.0 | 121.1 ± 20.4 | 120.9 ± 19.5 | 0.0042 |
| Diastolic blood pressure (mm Hg) | 72.8 ± 12.0 | 71.5 ± 11.7 | 70.7 ± 11.7 | <0.0001 |
| Total cholesterol (mg/dL) | 195.5 ± 37.9 | 197.6 ± 36.8 | 195.9 ± 36.0 | 0.0931 |
| HDL cholesterol (mg/dL) | 52.9 ± 12.8 | 54.8 ± 13.2 | 56.3 ± 13.6 | <0.0001 |
| Triglyceride (mg/dL) | 125.8 ± 83.0 | 120.8 ± 81.0 | 113.8 ± 74.1 | <0.0001 |
| Fasting glucose (mg/dL) | 94.4 ± 22.9 | 93.0 ± 18.6 | 92.8 ± 19.7 | <0.0001 |
| GGT (IU/L) | 19.5 ± 27.1 | 18.2 ± 18.5 | 17.8 ± 16.4 | <0.0001 |
| AST (IU/L) | 19.7 ± 17.0 | 19.1 ± 10.5 | 19.1 ± 8.9 | 0.0086 |
| ALT (IU/L) | 18.5 ± 22.0 | 17.8 ± 18.9 | 17.3 ± 12.7 | 0.0002 |
| % | % | % | ||
| Smoking status | ||||
| Ex-smoker | 2.3 | 2.6 | 2.4 | |
| Current smoker | 6.0 | 4.1 | 4.5 | <0.0001 |
| Alcohol intake (yes) | 27.4 | 27.7 | 30.8 | 0.0001 |
| Hypertension (yes) | 25.5 | 24.5 | 22.7 | 0.0002 |
| Diabetes (yes) | 4.9 | 5.3 | 4.6 | 0.6578 |
MET: metabolic equivalent of task; SD: standard deviation; HDL: high-density lipoprotein; GGT: γ-glutamyl transferase; AST: aspartate aminotransferase; ALT: alanine aminotransferase.