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. 2012 Nov 5;22(6):494–500. doi: 10.2188/jea.JE20110110

Table 2. Hazard ratios (95% CI) of cancer incidence, all-cause death, cancer death, and noncancer death by MET-min/week in mena .

  MET-min/week   ≥3.5 vs 0
MET-min/week

  0 3.5–1000 >1000 P for trend
  (n = 21 051) (n = 5808) (n = 4805)  
Cancer incidence          
Cases 1308 364 340    
Rateb 9.3 8.9 8.9    
Model 1 1.0 0.92 (0.81–1.04) 0.89 (0.79–1.01) 0.0465 0.90 (0.82–1.00)
Model 2 1.0 1.00 (0.84–1.13) 0.98 (0.84–1.13) 0.0030 0.99 (0.88–1.11)

All-cause death          
Cases 1083 219 214    
Rateb 8.2 5.6 6.8    
Model 1 1.0 0.70 (0.60–0.81) 0.66 (0.56–0.76) 0.0013 0.68 (0.60–0.76)
Model 2 1.0 0.73 (0.62–0.87) 0.66 (0.55–0.79) 0.0081 0.70 (0.61–0.79)

Cancer death          
Cases 539 99 122    
Rateb 3.9 2.7 3.3    
Model 1 1.0 0.66 (0.53–0.81) 0.79 (0.64–0.96) 0.1818 0.72 (0.62–0.85)
Model 2 1.0 0.72 (0.57–0.92) 0.78 (0.62–0.98) 0.4211 0.75 (0.63–0.90)

Noncancer death          
Cases 544 120 92    
Rateb 4.3 2.9 3.5    
Model 1 1.0 0.74 (0.60–0.91) 0.52 (0.41–0.66) 0.0016 0.63 (0.53–0.75)
Model 2 1.0 0.75 (0.59–0.95) 0.54 (0.41–0.70) 0.0036 0.64 (0.53–0.78)

aAdjusted for age, smoking status, alcohol intake, body mass index, hypertension, total cholesterol, and diabetes.

bAge-adjusted rate (per 100 000 person years).

Model 1: Without exclusion of early cases (those occurring within 3 years of the starting point).

Model 2: After exclusion of early cases (those occurring within 3 years of the starting point).