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. 2013 Oct 17;8(10):e77879. doi: 10.1371/journal.pone.0077879

Figure 5. Measurement of IFN-γ in the serum following treatment.

Figure 5

Groups of 5 C57BL/6 mice were mock-infected or infected IN with 106 pfu (~100 LD50s) of wt VACV. One day post infection mice were either mock-treated or treated with 107 pfu of v50ΔB13R or v50ΔB13RMγ. After 24 hours, serum was harvested and an ELISA was performed to measure IFN-γ. The horizontal line indicates the average and error bars indicate the standard error of the mean. Comparisons were done using the Mann-Whitney test. One asterisk (*) represents p<0.008 in comparison to the wt/v50ΔB13RMγ group. Two asterisks (**) represents p<0.016 in comparison to the wt/v50ΔB13RMγ group.