Table 4. Univariate regression coefficients for cancer death from a Cox proportional hazards regression model.
Dependent variable (increment) | Beta | SE | Hazard ratioc | 95% CI | P value |
HGF (0.09 ng/ml) | 3.949 | 1.185 | 1.44 | 1.16, 1.78 | <0.001 |
Age (10 years) | 0.072 | 0.013 | 2.14 | 1.62, 2.82 | <0.0001 |
Male sex | 0.919 | 0.295 | 2.51 | 1.41, 4.47 | 0.001 |
Body mass indexa (3 kg/m2) | −0.005 | 0.042 | 0.98 | 0.76, 1.27 | 0.894 |
Systolic BP (20 mm Hg) | 0.013 | 0.005 | 1.31 | 1.04, 1.66 | 0.024 |
Diastolic BP (11 mm Hg) | 0.009 | 0.011 | 1.11 | 0.87, 1.43 | 0.413 |
HbA1c (0.7%) | 0.280 | 0.100 | 1.24 | 1.07, 1.45 | 0.005 |
Blood urea nitrogen (1.4 mmol/l) | 0.058 | 0.029 | 1.27 | 1.01, 1.61 | 0.044 |
Creatinine (16.4 µmol/l) | 1.042 | 0.409 | 2.84 | 1.27, 6.32 | 0.011 |
Uric acid (59.4 µmol/l) | 0.101 | 0.090 | 1.15 | 0.90, 1.47 | 0.259 |
C-reactive proteinb (1.8 times) | 0.320 | 0.174 | 1.38 | 0.98, 1.94 | 0.066 |
Albumin (2 g/l) | −1.828 | 0.471 | 0.63 | 0.49, 0.79 | <0.001 |
Total cholesterol (0.87 mmol/l) | −0.015 | 0.004 | 0.58 | 0.44, 0.76 | <0.0001 |
HDL cholesterol (0.36 mmol/l) | −0.009 | 0.009 | 0.87 | 0.67, 1.14 | 0.327 |
Triglyceridesb (1.1 times) | −0.019 | 0.257 | 0.98 | 0.59, 1.62 | 0.940 |
AST (5 units/l) | −0.007 | 0.031 | 0.96 | 0.69, 1.33 | 0.813 |
ALT (3 units/l) | −0.033 | 0.051 | 0.89 | 0.63, 1.26 | 0.508 |
γ-GTPb (2.2 times) | 0.123 | 0.181 | 1.13 | 0.79, 1.61 | 0.496 |
Smoking | 0.828 | 0.288 | 2.29 | 1.30, 4.03 | 0.004 |
Alcohol | 0.422 | 0.287 | 1.53 | 0.87, 2.68 | 0.141 |
Antihypertensive medication | −0.127 | 0.347 | 0.88 | 0.45, 1.74 | 0.714 |
Antihyperlipidemic medication | 0.621 | 0.467 | 1.86 | 0.75, 4.66 | 0.183 |
Antidiabetic medication | 0.951 | 0.517 | 2.59 | 0.94, 7.15 | 0.066 |
Abbreviations: SE, standard error; HGF, hepatocyte growth factor; BP, blood pressure, HDL, high-density lipoprotein, AST, aspartate aminotransferase; ALT, alanine aminotransferase; γ-GTP, γ-glutamyl transpeptidase.
aWeight (kg)/height (m)2.
bThese variables are shown in the original scale after analysis using log (natural)-transformed values. These values indicate hazard ratios per times increase.
cHazard ratio per 1-increment increase in variable.