Table 3. Sex-specific age- and community-adjusted and multivariable-adjusted hazard ratios (95% CI) for incidence of cardiovascular events according to snoring frequency.
Snoring frequency | Men | Women | ||||||
Never | Sometimes | Daily | Unknown | Never | Sometimes | Daily | Unknown | |
Person-years | 2792 | 7014 | 3427 | 951 | 8462 | 11 715 | 2119 | 3268 |
Subjects (n) | 486 | 1144 | 561 | 159 | 1399 | 1900 | 352 | 512 |
Incident cardiovascular event (n) | 15 | 22 | 16 | 3 | 13 | 16 | 8 | 4 |
Incident ischemic heart disease (n) | 7 | 10 | 7 | 2 | 1 | 4 | 2 | 1 |
Incident stroke (n) | 8 | 12 | 9 | 1 | 12 | 12 | 6 | 3 |
Age- and community-adjusted HR (95% CI) |
(Reference) | 0.7 (0.4–1.4) |
1.1 (0.5–2.2) |
0.7 (0.2–2.3) |
(Reference) | 0.9 (0.5–2.0) |
2.6 (1.1–6.3) |
0.8 (0.2–2.4) |
Model 1 HR (95% CI)a | (Reference) | 0.7 (0.3–1.3) |
1.0 (0.5–2.1) |
0.7 (0.2–2.3) |
(Reference) | 0.9 (0.4–2.0) |
2.5 (1.0–6.1) |
0.8 (0.2–2.4) |
Model 2 HR (95% CI)b | (Reference) | 0.6 (0.3–1.3) |
1.0 (0.5–2.0) |
0.6 (0.2–2.3) |
(Reference) | 0.9 (0.4–1.9) |
2.1 (0.9–5.4) |
0.8 (0.2–2.4) |
Model 3 HR (95% CI)c | (Reference) | 0.6 (0.3–1.2) |
0.9 (0.4–1.9) |
0.6 (0.2–2.1) |
(Reference) | 0.8 (0.4–1.7) |
1.9 (0.8–4.9) |
0.7 (0.2–2.2) |
HR: hazard ratio; CI: confidence interval.
aModel 1 was adjusted for age, alcohol consumption, cigarette smoking, community, and, for women, menopausal status at baseline.
bModel 2 was adjusted for factors in Model 1 plus body mass index.
cModel 3 was adjusted for factors in Model 2 plus systolic blood pressure, antihypertensive medication use, diabetes mellitus, and hypercholesterolemia.