Table 2. Prevalence of Fabry disease by Japanese region, based on the number of beneficiaries identified from clinical research data as part of the Specified Disease Treatment Research Program and Japanese population data (2005 census).

	Males			Females			Total
Region of Japan	Number	Prevalencea	Standardized prevalence ratio	Number	Prevalencea	Standardized prevalence ratio	Number	Prevalencea	Standardized prevalence ratio
Hokkaido										1	0.04	0.12b	1	0.03	0.18b	2	0.04	0.15b
Tohoku										23	0.50	1.64b	13	0.26	1.45	36	0.37	1.57b
Kanto	69	0.33	1.00	43	0.21	1.15	112	0.27	1.06
Koshinetsu/ Hokuriku	20	0.48	1.58	10	0.23	1.28	30	0.35	1.47
Tokai	27	0.36	1.14	20	0.26	1.49	47	0.31	1.27
Kinki	21	0.21	0.66b	9	0.08	0.47b	30	0.14	0.59b
Chugoku	9	0.24	0.81	3	0.08	0.43b	12	0.16	0.66
Shikoku	6	0.31	1.03	6	0.28	1.56	12	0.29	1.24
Kyushu	22	0.32	1.02	12	0.15	0.87	34	0.23	0.95
Total	198	0.32		117	0.18		315	0.25

^aPer 100 000 individuals in 2005.

^bSignificantly higher or lower (P < 0.05).