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Effect of sodium-free BR perfusion on pHi in SLC4A11-transfected HEK293. A: pHi responses to Na free perfusion in BR for SLC4A11 or empty vector (control)-transfected HEK293 cells. Traces represent the average of 6 experiments. B: summary of rates of acidification (Na+-free). C: extent of acidification. D: rate of alkalinization (Na+ add back). E: extent of alkalinization.
