Table 3.
Morphometric data and myocardial hydroxyproline concentration.
| SHAM (n = 8) | Myocardial infarction (n = 13) | p-value | |
| LVW/BW, (g/kg) | 1.76±0.17 | 2.11±0.57 | 0.110 |
| RVW/BW, (g/kg) | 0.39 (0.36-0.43) | 0.54 (0.47-1.04) | <0.001 |
| Lung WC, (%) | 76.2 (72.1-77.3) | 75.4 (73.5-77.2) | 0.913 |
| Liver WC, (%) | 68.4 (66.1-69.0) | 67.7 (67.4-68.0) | 0.205 |
| IC*), (%) | 1.85±0.70 | 4.02±0.61 | <0.001 |
| CSA*), (μm2) | 306±53 | 493±65 | <0.001 |
| HOP**, (μg/mg) | 3.32±0.75 | 5.48±0.73 | 0.002 |
*
7 rats per group; ** 5 rats per group. SHAM: rats subjected to surgery but without coronary occlusion; BW: body weight; LVW: left ventricular weight; RVW: right ventricular weight; WC: water content; IC: interstitial collagen volume fraction; CSA: myocyte cross-sectional area; HOP: hydroxyproline. Data are expressed as means±SD or medians (25%-75%).