Table 1.

Tissue masses and lipid levels after 16 wk of LF or HF diet

	Total Fat Mass, g	Epididymal Fat Mass, g	Lean Tissue Mass, g	Liver Mass, g	Liver TG, μg/mg	Serum Cholesterol, mg/dl	Serum TG, mg/dl
LF
WT (n = 10)	3.89 ± 1.78	0.68 ± 0.26	20.54 ± 1.44	1.37 ± 0.29	13.32 ± 1.30	75.68 ± 3.80	47.14 ± 1.19
CCR5−/− (n = 8)	2.71 ± 0.74	0.45 ± 0.14	19.61 ± 2.04	1.20 ± 0.23	14.33 ± 5.09	59.65 ± 9.32	47.33 ± 2.86
HF
WT (n = 36)	17.32 ± 3.22*	2.13 ± 0.50*	24.19 ± 3.23*	2.31 ± 0.72**	113.50 ± 10.90**	130.30 ± 7.86**	51.21 ± 2.54
CCR5−/− (n = 39)	17.13 ± 3.61*	2.10 ± 0.51*	23.72 ± 2.57*	2.16 ± 0.58**	105.00 ± 8.67**	127.30 ± 9.05**	45.25 ± 2.32

Data are the mean ± SE of the no. of mice in each group. LF, low fat; HF, high fat; TG, triglyceride; WT, wild type; CCR5, C-C chemokine receptor 5. WT and CCR5^−/− mice were placed on a LF or HF diet for 16 wk.

^*P < 0.05;

^**P < 0.001, diet effect for comparison with respective LF groups