Table 3. Variants detected in mtDNA of African-American POAG cases and controls, but not found in the MITOMAP or PhyloTree databases.
Group | Variant | Locus | AA change | Substitution type | Likely pathogenic? |
---|---|---|---|---|---|
POAG | m.8274C>T | Non-coding 7 | - | Transition | No |
m.11813C>T | ND4 | Leu>Phe | Transition | No | |
m.12266A>G | tRNA-Leu | - | Transition | No | |
Control | m.10694A>T | ND4L | Syn. | Transversion | No |