Fig. 6.

NO-mediated inhibition of TC uptake but not MTSET-mediated inhibition of TC uptake occurs through C96. A: cells were transfected with C96A Ntcp. Later (48 h), cells were treated with or without 1 mM MTSET for 30 min, and then relative TC uptake was determined. Data are expressed as means ± SE (n = 3). *Significantly different from untreated sample (P < 0.05). B: cells were transfected with C96A Ntcp. Later (48 h), cells were treated with or without various doses of CysNO (0.0625–1 mM) for 30 min, and then relative TC uptake was determined. Data are expressed as means ± SE (n = 3). *Significantly different from WT Ntcp control values (P < 0.05).