Table 1.

Selected urinary parameters and serum oxalate in DRA KO mice and their WT littermates

	WT	KO
Urine volume, ml/24 h	0.80 ± 0.12	0.68 ± 0.10
Urine pH	6.11 ± 0.01	5.29 ± 0.09*
Urinary oxalate excretion, μmol/24 h	1.64 ± 0.16	0.50 ± 0.06*
Urinary Ca2+ excretion, μmol/24 h	1.42 ± 0.19	1.71 ± 0.26
Urinary creatinine excretion, μmol/24 h	5.75 ± 0.44	6.06 ± 0.51
Serum oxalate, μmol/l	11.61 ± 2.30	4.65 ± 1.76*

Values are means ± SE of duplicate measurements of 12–20 urine pools in each group with 2 mice per pool. Serum oxalate was measured in 11 wild-type (WT) and 8 DRA (downregulated in adenoma) knockout (KO) pools with 2–5 mice per pool.

^*Significantly different from WT (P ≤ 0.05).