Table 2.
Brain region | No. of voxels | Zmax | Talairach coordinates | Correlation | |||||
---|---|---|---|---|---|---|---|---|---|
x | y | z | r | rpartial | |||||
Age | WM1 | Speed2 | |||||||
Left middle temporal gyrus | 214 | 4.41 | −56 | −14 | −8 | 0.78** | 0.73* | 0.73* | 0.74* |
Left middle temporal gyrus | 114 | 3.66 | −52 | −70 | 0 | 0.74** | 0.66* | 0.68* | 0.70* |
Right middle temporal gyrus | 291 | 4.50 | 58 | −66 | 0 | 0.84** | 0.78** | 0.77* | 0.88** |
Right middle temporal gyrus | 133 | 4.37 | 60 | −42 | 0 | 0.81** | 0.75** | 0.83** | 0.80** |
Right superior parietal lobule | 352 | 4.11 | 38 | −50 | 58 | 0.80** | 0.76** | 0.76* | 0.80** |
Right lateral bank of IPS—IPS | 176 | 3.84 | 52 | −54 | 46 | 0.76** | 0.67* | 0.77* | 0.71* |
Right middle occipital gyrus | 201 | 4.79 | 38 | −90 | 0 | 0.85** | 0.85** | 0.82** | 0.84** |
Right middle cingulum | 335 | 3.90 | 8 | −30 | 44 | 0.77** | 0.65* | 0.70* | 0.71* |
Brain regions corresponded to activation peaks, obtained from random-effect analysis using a threshold of P < 0.001, uncorrected, at the voxel level and P < 0.05, corrected for multiple comparisons, at the cluster level. Both simple positive correlations (r) and partial positive correlations (r partial, i.e., corrected for variance explained by age, working memory, and processing speed measures) are reported. Coordinates are reported in MNI space as given by SPM2 and correspond only approximately to Talairach and Tournoux space (Talairach and Tournoux, 1988). Anatomical labels are based on the AAL (automated anatomical labeling) atlas (Tzourio-Mazoyer et al., 2002).
P < 0.01,
P < 0.001.
Working memory measures (forward and backward visuospatial, verbal, and listening spans).
Processing speed measures (mean RTs for numerical or color comparisons, mean RTs across tasks).