Fig. 4.

70% Oxygen exposure decreases the abundance of small-circular airspaces in the periphery of sGC-α1 KO lungs. The log area and circularity (LArC) of peripheral airspace structures of toluidine blue-stained inflation-fixed P13 mouse pup lung images was measured, binned, and arranged in a heat map. Circularity ranges from 1 (round) to 0 (oblong); log area corresponds to structures with areas between 64 and 2,500 μm². The number of airspaces classed per bin ranges from low (dark blue) to high (dark red) according to the scale on the right. The lungs from 12 pups per group were analyzed. The distributions of airspace structures were different in the groups by χ² analysis.