Fig. 3.

Renal denervation reduces albuminuria independently of blood pressure in SLE mice. A: mean arterial blood pressure (mmHg) was significantly elevated in SLE mice compared with controls (n = 4–8). Renal denervation (Dnx) had no effect in either group. *P < 0.05 vs. corresponding Control. B: urinary albumin (μg/mg creatinine) was increased in SLE mice compared with controls (n = 6–9). Renal denervated SLE mice had urinary albumin levels comparable to control sham and control Dnx mice. The horizontal line represents the geometric mean for each group. The impact of Dnx on albuminuria was statistically significant (*P < 0.04).