Fig. 5.
Temporal changes in renal hemodynamics in control and STZ (50 mg/kg ip)-treated Dahl SS rats with a low dose (2 U/day sc) of insulin during 12 wk of diabetes: renal blood flow (RBF; ml·min−1·g kidney wt−1) (A), glomerular filtration rate (GFR; μl·min−1·g kidney wt−1) (B), filtration fraction (FF; %) (C), and renal vascular resistance (RVR; mmHg·ml−1·min·g kidney wt) (D). The number of rats studied was 5–8 animals per group. Values are expressed as means ± SE. *Significant difference from the corresponding value within the same group at week 0. †Significant difference from the corresponding value in Control SS rats within the same time period.