Table 1.
Effects of inhalation of NaHS and its vehicle on the baselines of CSLV fiber activity, mean arterial blood pressure, and heart rate in anesthetized, artificially ventilated rats
| Vehicle of NaHS (n = 24) | NaHS (n = 72) | |
|---|---|---|
| CSLV fiber activity, impulses/s | ||
| Before inhalation | 0.05 ± 0.02 | 0.04 ± 0.01 |
| 5 Min after inhalation | 0.06 ± 0.02 | 0.06 ± 0.01 |
| 30 Min after inhalation | 0.05 ± 0.02 | 0.04 ± 0.01 |
| Mean arterial blood pressure, mmHg | ||
| Before inhalation | 85 ± 5 | 81 ± 3 |
| 5 Min after inhalation | 78 ± 5 | 83 ± 3 |
| 30 Min after inhalation | 83 ± 5 | 84 ± 3 |
| Heart rate, beats/min | ||
| Before inhalation | 349 ± 14 | 334 ± 9 |
| 5 Min after inhalation | 337 ± 16 | 317 ± 9 |
| 30 Min after inhalation | 337 ± 15 | 333 ± 10 |
Data (means ± SE) are values averaged over 10-s periods before and 5 min and 30 min after the termination of inhalation. n represents fiber numbers. Lungs were exposed to aerosolized NaHS (5 mg/ml) or its vehicle for 3 min. Only one capsaicin-sensitive lung vagal (CSLV) fiber was studied in each rat. No statistical significance was found between any 2 groups of mean.