Table 2.
Toxicity parameters of other nanoparticles tested in adult fish and eggs of zebrafish Danio rerio and teratogenicity of these nanoparticles.
| Nanoparticle | Stage | n | 48-h LC50mg/L | 96-h LC0mg/L | 96-h LC50mg/L | 96-h LC100 mg/L | Teratogenicity |
|---|---|---|---|---|---|---|---|
| Calcium phosphateamorphous <100 nm | adult | 20 | >1600.0 | ND | >1600.0 | ND | |
| eggs | 20 | >1600.0 | ND | >1600.0 | ND | no | |
| Calcium oxide(CaO) <160 nm | adult | 30 | 260.0 | 100.0 | 260.0 | 400.0 | |
| eggs | 30 | 290.0 | 200.0 | 290.0 | 400.0 | no | |
| Carbon(C) <50 nm | adult | 20 | >1600.0 | ND | >1600.0 | ND | |
| eggs | 20 | >1600.0 | ND | >1600.0 | ND | no | |
| Carbon nanotube7-15×3–6×0.5–200 nm | adult | 20 | >200.0 | ND | >200.0 | ND | |
| eggs | 20 | >200.0 | ND | >200.0 | ND | no | |
| Fullerene(C60) | adult | 20 | >200.0 | ND | >200.0 | ND | |
| eggs | 20 | >200.0 | ND | >200.0 | ND | no | |
| Hydroxyapatite (Ca5HO13P3) <200 nm | adult | 20 | >1600.0 | ND | >1600.0 | ND | |
| eggs | 20 | >1600.0 | ND | >1600.0 | ND | no | |
| Silicon nitride(Si3N4) <50 nm | adult | 20 | >1600.0 | ND | >1600.0 | ND | |
| eggs | 20 | >1600.0 | ND | >1600.0 | ND | no | |
| Silicon dioxide(SiO2) | adult | 20 | >1600.0 | ND | >1600.0 | ND | |
| eggs | 20 | >1600.0 | ND | >1600.0 | ND | no |
LC100 - minimum concentration causing 100% mortality; LC0 - maximum concentration causing no mortality; ND - not determined; n - number of fish used for calculation of LC50 value; no – concentration ≤100 mg/L causing no teratogenicity