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. 2013 Sep 24;5(9):1664–1681. doi: 10.3390/toxins5091664

Figure 1.

Figure 1

Pasteurella multocida toxin (PMT)-dependent signaling pathways. PMT modifies the Gα subunits of the heterotrimeric G proteins Gαi, Gαq/11 and Gα12/13 through deamidation. The major subsequent signaling pathways are depicted according to the activated Gα subunit. The cellular outcomes are described in the shaded boxes.