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. 2013 Oct 18;3:2381. doi: 10.1038/srep02381

Figure 4. Detection of DNA containing different numbers and distribution of methylated cytosines.

Figure 4

(a), (b) and (c) compared the duration of short and long signature blocks for targets Tp16-1 (a), Tp16-2 (b) and Tp16-3 (c) detected by four probes PC6, PC8, PC14 and PC16. The duration of signature blocks allowed determining the methylation status for each of four CpG cytosines. The DNA sequences of the three p16 fragments were given in Table S1. Duration values were given in Table S3. All traces were recorded at +130 mV in 1 M KCl and 10 mM Tris (pH 7.4).