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. 2013 Sep 17;5(9):3684–3695. doi: 10.3390/nu5093684

Table 2.

Change in vitamin C intake and ascorbate concentration in body fluids, cells and tissue following supplementation with 50 mg vitamin C or half a kiwifruit per day for six weeks.

Vitamin C group a (50 mg/day) Kiwifruit group a (half/day) Between group
Baseline Intervention Washout Baseline Intervention Washout Intervention
P value b
Intake (mg/day) 31.2 ± 3.1 76.7 ± 2.6 *** 29.1 ± 2.9 28.6 ± 3.1 73.4 ± 4.2 *** 31.4 ± 5.1 0.512
Plasma (µmol/L) 23.5 ± 2.5 51.3 ± 3.5 *** 34.3 ± 4.4 * 22.7 ± 2.5 45.5 ± 2.5 *** 30.5 ± 3.1 0.860
Urine (µmol/24 h) 42.8 ± 9.2 104.2 ± 27.6 * 59.5 ± 19.9 32.3 ± 8.1 70.5 ± 17.0 * 64.7 ± 29.8 0.503
Semen (µmol/L) 284.8 ±27.0 321.0 ± 33.3 264.4 ± 31.1 * 326.3 ± 47.5 378.8 ± 42.7 237.7 ± 19.6 * 0.676
Mononuclear cells (nmol/108 cells) 38.7 ± 6.2 84.5 ± 6.3 *** 78.5 ± 4.3 ** 60.5 ± 6.1 90.9 ± 6.1 ** 75.2 ± 5.2 0.227
Neutrophils (nmol/108 cells) 21.9 ± 3.1 39.6 ± 3.8 ** 24.9 ± 2.1 13.7 ± 2.4 30.4 ± 2.5 *** 24.8 ± 1.7 *** 0.798
Skeletal muscle (nmol/g) 14.5 ± 2.0 61.3 ± 3.5 *** nd 15.1 ± 2.5 52.8 ± 5.0 *** nd 0.429

a Data represent mean ± SEM; b P values were determined by unpaired t-test of vitamin C group versus kiwifruit group post-intervention following subtraction of baseline values; * P < 0.05 and ** P < 0.01 and *** P < 0.001 for paired t-test of intervention versus baseline. nd = not determined.