Table 1. PICT1 expression and clinocopathologic factors in gastric cancer patients with wild-type TP53.
| |
PICT1
low expression (n=35) |
PICT1
high expression (n=35) |
|
||
|---|---|---|---|---|---|
| Factors | Number | % | Number | % | P-value |
| Age (mean±s.d.) |
66.5±2.00 |
|
64.5±2.00 |
|
0.477 |
|
Gender | |||||
| Male | 22 | 62.9 | 21 | 60.0 | 0.806 |
| Female |
13 |
37.1 |
14 |
40.0 |
|
|
Histological grade | |||||
| Well and moderately | 17 | 48.6 | 18 | 51.4 | 0.811 |
| Poorly and Signet |
18 |
51.4 |
17 |
48.6 |
|
|
Tumour deptha | |||||
| m, sm, mp | 21 | 60.0 | 12 | 34.3 | 0.03* |
| ss, se, si |
14 |
40.0 |
22 |
65.7 |
|
|
Lymph node metastasis | |||||
| Absent | 16 | 45.7 | 17 | 48.6 | 0.811 |
| Present |
19 |
54.3 |
18 |
51.4 |
|
|
Lymphatic invasion | |||||
| Absent | 13 | 37.1 | 9 | 25.7 | 0.302 |
| Present |
22 |
62.9 |
26 |
74.3 |
|
|
Venous invasion | |||||
| Absent | 32 | 91.4 | 26 | 74.3 | 0.052 |
| Present |
3 |
8.6 |
9 |
25.7 |
|
|
Peritoneal dissemination | |||||
| Absent | 34 | 97.1 | 30 | 85.7 | 0.075 |
| Present |
1 |
2.9 |
5 |
14.3 |
|
|
Stage | |||||
| Stages I, II | 26 | 74.3 | 19 | 54.3 | 0.081 |
| Stages III, IV | 9 | 25.7 | 16 | 45.7 | |
*P<0.05.
a
Tumour invasion of mucosa (m), submucosa (sm), muscularis propria (mp), subserosa (ss), penetration of serosa (se), and invasion of adjacent strucures (si).