Figure 4.

Upregulation of HLA-DR expression in HNSCC by EGFR inhibitors. (A) HLA-DR expression of HNSCC cell lines was examined by flow cytometry. HNSCC cells were treated with IFN-γ (50 U ml⁻¹) alone or with IFN-γ and elrotinib (1 mM) for 48 h. (B) HLA-DR expression of HNSCC cell lines was examined by flow cytometry. HNSCC cells were treated with IFN-γ (50 U/ml) alone or with IFN-γ and cetuximab (2 mg ml⁻¹) for 48 h.