Table 1.
Patient | Age/Sex | CTC Count | Tumor Stage | CTC KRAS Status | Biopsy KRAS Status/Method | Treatment | Disease State | Total Cell Count | Time from Biopsy to CTC Collection (Days) |
1 | 61/F | 16 | I | G12D | Not tested/N/A | N/A | N/A | 2050 | N/A |
2 | 64/M | 17 | IV | Wild type | Wild type/PCR | Avas & Fol/Ava, 5-FU, Leu/Cli | Stable | 1659 | 2120 |
3 | 49/F | 93 | II | Wild type | Wild type/Sanger | None | N/A | 12,911 | 1 |
4 | 54/M | 600 | IV | Wild type | Wild type/PCR | Lav, 5-FU/FOL/Fol, Erb/Cli/FOL | Progressive | 7314 | 699 |
5 | 58/F | 7 | IV | G13D | Wild type/Sanger | FOL | N/A | 1129 | 148 |
6 | 71/M | 71 | IV | G12D, G12A | G12C/PCR | 5-FU | N/A | 3462 | 1098 |
7 | 73/M | 23 | IIIB | G13D | Wild type/Sanger | FOL/5-FU, Leu/Fol/FOL/5-FU, Eu/Cli/5-FU | Progressive (expired) | 1389 | 69 |
8 | 59/M | 0 | IV | Wild type | Wild type/Sanger | FOL, Ava/Fol, Erb/Cli | Stable | 1148 | 994 |
9 | 67/M | 18 | IV | Wild type | Wild type/Sanger | Oxa/Cli | N/A | 5040 | 337 |
10 | 62/M | 83 | II | G13D | Wild type/Sanger | 5-FU | N/A | 2484 | 74 |
11 | 69/M | 27 | II | Wild type | Wild type/Sanger | 5-FU | N/A | 2213 | 1076 |
12 | 26/F | 56 | IV | Wild type | G13D/Sanger | FOL, bev/Fol, bev | Progressive | 1729 | 223 |
13 | 63/M | 82 | III | G13D | Wild type/Sanger | FOL/Fol/5-FU, Leu/Fol, Ava/FOL, Ava | Progressive | 887 | 414 |
14 | 64/M | 0 | IV | Wild type | Wild type/Sanger | 5-FU, radiation/FOL/FOL, Ava | Partial response | 924 | 670 |
15 | 75/M | 18 | IIB | G13D | Wild type/PCR | None | N/A | 1098 | 1 |
Treatments administered: Folfiri (Fol), FOLFOX (FOL), 5-FU, Avastin (Ava), Leucovorin (Leu), bevacizumab (bev), Erbitux (Erb), cetixumab (cet), or clinical trial participation (Cli).