Table 1.
Fusion Transcripts Experimentally Validated by RT-PCR and Sanger Sequencing.
| Fusion Gene | Chromosome | Bands | Cell Line | Distance (kb)* | Genomic Breakpoint† |
| Interchromosomal | |||||
| SLC39A14-TSPAN15 | 8p21.3 | 10q22.1 | HT29 | N | |
| NCOA3-SPINT1 | 20q12 | 15q13.3 | HCT15 | N | |
| GRIN2B-CYP4F3 | 12p12 | 19p12.12 | SW480 | Y | |
| FAM96A-STIM1 | 15q22.31 | 11p15.5 | SW480 | Y | |
| Intrachromosomal | |||||
| PRMT1-FLT3LG | 19q13.33 | 19q13.33 | HCT15 | 214 | N |
| MGRN1-C16orf96 | 16p13.3 | 16p13.3 | HCT15 | 134 | Y |
| COMMD10-AP3S1 | 5q23.1 | 5q22.3 | HCT116 | 198 | Y |
| SPAG9-MBTD1 | 17q21.33 | 17q21.33 | HCT116 | 298 | Y |
| AKAP13-PDE8A | 15q25.3 | 15q25.3 | SW480 | 556 | N |
| CTB-35F21.1-PSD2 | 5q31.2 | 5q31.2 | SW480 | 160 | N |
*
Distance is the outer distance between the two genes.
†
Predicted genomic breakpoint by nFuse.