TABLE 6.
[3H]Dihydromorphine Binding | |||
---|---|---|---|
fmol/mg protein | fmol/mg protein | ||
Cerebral hemispheres | Extrapyramidal areas | ||
Frontal pole | 11.9 | Caudate nucleus (head) | 19.4 |
Superior temporal gyrus | 10.1 | Caudate nucleus (body) | 9.0 |
Middle temporal gyrus | 7.1 | Caudate nucleus (tail) | 8.9 |
Inferior temporal gyrus | 6.0 | Putamen | 11.7 |
Precentral gyrus | 3.4 | Globus | 7.7 |
Postcentral gyrus | 2.8 | Internal capsule | 5.4 |
Occipital pole | 2.3 | Midbrain | |
White matter areas | Superior colliculi | 10.6 | |
Corpus callosum | <2 | Inferior colliculi | 6.7 |
Corona radiata | <2 | Interpeduncular nucleus | 13.7 |
Anterior commissure | 5.4 | Raphe area | 8.2 |
Fornix | <2 | Periaqueductal gray | 31.1 |
Optic chiasm | <2 | Cerebellum-lower brain stem | |
Limbic cortex | Pons (ventral) | 1.4 | |
Anterior amygdala | 65.1 | Cerebellar cortex | <2 |
Posterior amygdala | 34.1 | Dentate nucleus | 1.9 |
Hippocampus | 12.5 | Floor of fourth ventricle | 6.3 |
Hypothalamus | Pyramidal tract | 3.0 | |
Medial hypothalamus | 24.2 | Lower medulla | 5.8 |
Anterior hypothalamus | 24.3 | Spinal cord (thoracic) | |
Posterior hypothalamus | 24.7 | Dorsal column (white) | 3.1 |
Hypothalamus | 32.2 | Lateral cord (white) | 3.3 |
Mammillary bodies | 5.0 | Gray matter | 8.8 |
Thalamus | |||
Medial thalamus | 24.6 | ||
Lateral thalamus | 7.8 |