Fig. 2.
Dark exacerbates superoxide generation by retina in diabetic mice. Superoxide was measured (lucigenin method) 7 h after lights came on (daylight) and 7 h after lights went off (darkness) in N and D wild-type mice. Samples collected during the night were collected under dim red light. Duration of diabetes was 2 mo at the time of this assay (n = 5 per group, 4 mo of age when killed).