Table 2.
These factors are known to be involved in myogenesis
| TF name | TRANSFAC id | No. of promoters with z-score | Consensus from TRANSFAC | Significant positions with P-values | |
|---|---|---|---|---|---|
| NFAT1 | M01281 | 1123 (44.14) | GGAAAA | −39 (=0.0009199) | (46) |
| Pitx2 | M00482 | 735 (77.48) | WNTAATCCCAR | −27 (<2.2e-16) | (47) |
| −23 (<2.2e-16) | |||||
| −11 (<2.2e-16) | |||||
| 10 (<2.2e-16) | |||||
| 22 (=7.332e-15) | |||||
| 26 (<2.2e-16) | |||||
| MAZ | M00649 | 613 (55.13) | GGGGAGGG | −42 (=0.02665) | (48) |
| −34 (=0.02665) | |||||
| 29 (=0.006371) | |||||
| 41 (=0.01854) | |||||
| 44 (=0.01854) | |||||
| Meis2 | M01488 | 521 (7.73) | NANNASCTGTCAAWNN | −2 (<2.2e-16) | (49) |
| 2 (<2.2e-16) | |||||
| MEIS1 | M00419 | 521 (12.29) | NNNTGACAGNNN | −3 (<2.2e-16) | (50) |
| 3 (<2.2e-16) |
The table summarizes the top significantly co-occurring factors with MyoD in >500 promoters and are not identical to the MyoD motif pattern. The positions in the last right column are identified to be significant after comparing with the background; only those positions that have z-score above 10 and P-value below 0.005 were selected.